Triple agonism based therapies for obesity (review
I actually think if people just got the first hour of their day more active and energized bright light, exercise, caffeine if youre me, and Lord knows Im grateful that caffeine exists in the first hour of the day, or first hours if you cant manage that because of schedule, and then the last hour of the day was strongly parasympathetic, everything would get better without having to think a ton about exactly how youre doing that, because on a given day, you just do what you can
The colonic lining primarily absorbs water and electrolytes, and introducing coffee repeatedly can disrupt the delicate balance of the intestinal microbiome and damage protective mucosal barriers
Zelenak C, Eberhard M, Jilani K, Qadri SM, Macek B, Lang F